Isoprenylcysteine Carboxyl Methyltransferase Activity Modulates Endothelial Cell Apoptosis
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چکیده
منابع مشابه
Isoprenylcysteine carboxyl methyltransferase modulates endothelial monolayer permeability: involvement of RhoA carboxyl methylation.
RhoA and Rac1 regulate formation of stress fibers and intercellular junctions, thus modulating endothelial monolayer permeability. Posttranslational modifications of RhoA and Rac1 regulate enzyme activity and subcellular localization, resulting in altered cellular function. The role of RhoA and Rac1 carboxyl methylation in modulating endothelial monolayer permeability is not known. In this stud...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2003
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e02-07-0390